Powder: -20°C for 3 years In solvent: -80°C for 2 years
MST-312 是一种端粒酶抑制剂，可用于多发性骨髓瘤等癌症研究。
| 产品描述 | MST-312 is an inhibitor of telomerase and can be used in studies about cancer, such as multiple myeloma. |
| 体外活性 | In U-266 cells, MST-312 (2 μM) upregulates the pro-apoptotic gene Bax and down-regulates the anti-apoptotic gene Bcl-2 and suppresses the expression of c-Myc and hTERT genes. MST-312 (2-8 μM) reduces cellular viability in a dose dependent and time-dependent manner. MST-312 (2-8 μM) induces cell apoptosis in a dose-dependent manner[1]. |
| 别名 | Telomerase Inhibitor IX |
| 分子量 | 380.356 |
| 分子式 | C20H16N2O6 |
| CAS No. | 368449-04-1 |
Powder: -20°C for 3 years In solvent: -80°C for 2 years
DMSO: 70 mg/mL (184.04 mM), ultrasonic and warming and heat to 60°C
( < 1 mg/ml refers to the product slightly soluble or insoluble )
参考文献
剂量换算对于不同动物的给药剂量换算，您也可以参考 更多
体内实验配液计算器计算器bottom
您可能有的问题的答案可以在抑制剂处理说明中找到，包括如何准备库存溶液，如何存储产品，以及基于细胞的分析和动物实验需要特别注意的问题。
MST-312 368449-04-1 DNA Damage/DNA Repair Telomerase EGCG epigallocatechin gallate Inhibitor multiple tea derivative cancer MST 312 inhibit MST312 myeloma Telomerase Inhibitor IX inhibitor
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