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顶部相关产品产品介绍化学信息储存和溶解信息计算器

(±)5-iPF2α-VI

Synonyms: (±)5-iPF2α-VI
货号 T36605Cas号 179094-11-2 一键复制产品信息
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Isoprostanes are prostaglandin (PG)-like products of free-radical induced lipid peroxidation. Although the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can form isoprostanes. (±)5-iPF2α-VI is one of dozens of possible stereo- and regioisomeric isoprostanes which can be formed from arachidonic acid. To date, the most extensively studied of these is 8-isoprostane (8-epi-PGF2α, iPF2α-III). However, 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers which form in natural conditions of oxidative stress. (±)5-iPF2α-VI is an isoprostane from the unique Type VI class of isoprostanes. This class has been shown to be one of the major isoprostane products, in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane, Type VI isoprostanes form internal lactones, which facilitates their extraction and purification from biological samples.

(±)5-iPF2α-VI

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货号 T36605Cas号 179094-11-2

别名 (±)5-iPF2α-VI

Isoprostanes are prostaglandin (PG)-like products of free-radical induced lipid peroxidation. Although the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can form isoprostanes. (±)5-iPF2α-VI is one of dozens of possible stereo- and regioisomeric isoprostanes which can be formed from arachidonic acid. To date, the most extensively studied of these is 8-isoprostane (8-epi-PGF2α, iPF2α-III). However, 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers which form in natural conditions of oxidative stress. (±)5-iPF2α-VI is an isoprostane from the unique Type VI class of isoprostanes. This class has been shown to be one of the major isoprostane products, in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane, Type VI isoprostanes form internal lactones, which facilitates their extraction and purification from biological samples.

(±)5-iPF2α-VI
规格价格库存数量
10 μg
¥ 1,430
35日内发货
25 μg
¥ 3,390
35日内发货
50 μg
¥ 6,390
35日内发货
100 μg
¥ 11,300
35日内发货
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产品介绍

生物活性
产品描述
Isoprostanes are prostaglandin (PG)-like products of free-radical induced lipid peroxidation. Although the isoprostanes derived from arachidonic acid are the best characterized, many other polyunsaturated fatty acids can form isoprostanes. (±)5-iPF2α-VI is one of dozens of possible stereo- and regioisomeric isoprostanes which can be formed from arachidonic acid. To date, the most extensively studied of these is 8-isoprostane (8-epi-PGF2α, iPF2α-III). However, 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers which form in natural conditions of oxidative stress. (±)5-iPF2α-VI is an isoprostane from the unique Type VI class of isoprostanes. This class has been shown to be one of the major isoprostane products, in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane, Type VI isoprostanes form internal lactones, which facilitates their extraction and purification from biological samples.
别名
(±)5-iPF2α-VI
化学信息
分子量354.487
分子式C20H34O5
CAS No.179094-11-2
SmilesCCCCC\C=C/C[C@H]1[C@H](O)C[C@H](O)[C@H]1\C=C\C(O)CCCC(O)=O
密度1.153 g/cm3 (Predicted)
储存&溶解度
存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息
DMF: 50 mg/mL (141.05 mM), Sonication is recommended.
DMSO: 50 mg/mL (141.05 mM), Sonication is recommended.
Ethanol: 50 mg/mL (141.05 mM), Sonication is recommended.
PBS (pH 7.2): 0.5 mg/mL (1.41 mM), Sonication is recommended.
溶液配制表
PBS (pH 7.2)/DMF/DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.8210 mL14.1049 mL28.2098 mL141.0489 mL
DMF/DMSO/Ethanol
1mg5mg10mg50mg
5 mM0.5642 mL2.8210 mL5.6420 mL28.2098 mL
10 mM0.2821 mL1.4105 mL2.8210 mL14.1049 mL
20 mM0.1410 mL0.7052 mL1.4105 mL7.0524 mL
50 mM0.0564 mL0.2821 mL0.5642 mL2.8210 mL
100 mM0.0282 mL0.1410 mL0.2821 mL1.4105 mL
该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

5-iPF2α-VI5-iPF2a-VI5-iPF2alpha-VI(±)5-iPF-2α-VI(±)5iPF2αVI(±)5 iPF2α VI
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