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zolmitriptan

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  • 抑制剂&激动剂
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    TargetMol | Inhibitors_Agonists
  • Zolmitriptan
    佐米曲普坦, BW-311C90, 311C90
    T1092139264-17-8
    Zolmitriptan (311C90) 是一种5-HT1B 1D 受体部分激动剂,可用于偏头痛的研究,对 5-HT1B、5-HT1D、5-HT1F 受体的Ki 分别为 5.01、0.63 和 63.09 nM。
    • ¥ 327
    In stock
    规格
    数量
  • N-desmethyl Zolmitriptan
    T36063139264-35-0
    N-desmethyl Zolmitriptan (DZT) is an active metabolite of the serotonin (5-HT) receptor subtype 5-HT1B and 5-HT1D agonist zolmitriptan . DZT is an agonist of 5-HT1B receptors that induces contraction of isolated human cerebral arteries (EC50 = 100 nM).
    • ¥ 14700
    35日内发货
    规格
    数量
  • Decarbonyl zolmitriptan
    T70784139264-69-0
    is a compound related to Zolmitriptan (Z639000), which is Serotonin 5HTID-receptor agonist.
    • ¥ 10600
    6-8周
    规格
    数量
  • PF-05139962
    T707821393712-18-9
    PF-05139962 is a novel potent mTOR inhibitor with excellent mTOR biochemical inhibition, cellular potency, kinase selectivity and in vitro ADME properties. PF-05139962 has pS473 and pS6 cellular IC50 = 48 and 6 nM respectively. PF-05139962 has great selectivity against other receptors and kinases. No genotoxicity was observed on this compound and no more than 25% inhibiton was observed for major CYP enzymes (3A4, 1A2, 2C9, 2D6) at 3 uM. This compound has LE = 0.35 and LipE up to 6.8 which is in a very desirable range for a kinase inhibitor.
    • ¥ 10600
    6-8周
    规格
    数量