yangambin

Yangambin 是从诸如番荔枝科植物中分离出来的呋喃木脂素，是选择性PAF 受体拮抗剂，通过调控Ca2+通道抑制 Ca2+流入，导致 [Ca2+]i 在血管平滑肌细胞和随后的外周血管舒张中减少，具有降压作用。

Epiyangambin is a phytotoxic lignan, it shows inhibition of seed germination of Agrostis stolonifera cv. penncross (Poaceae) and inhibition of development of Lactuca sativa L. (Asteraceae) seedlings in a microassay using 24-well plates. Epiyangambin exhibits significant inhibition of the transformation of murine epidermal JB6 cells, with the IC50 value of 0.15 microg mL. (+)-Epiyangambin also has anti-platelet aggregation activity.

Diayangambin (Syringaresinol dimethyl ether; Lirioresinol C dimethyl ether) 作为一种细胞增殖抑制剂，其对人单核细胞的IC50值为1.5 μM。此外，Diayangambin 还表现出免疫抑制与抗炎特性。

De-4'-O-methylyangambin exhibits antibacterial effects. It also has analgesia activity.