wnk in 3

WNK-IN-3 is a novel allosteric inhibitor of WNK kinase.

WNK-IN-11-D3 is an effective,selective,and orally active WNK1 kinase inhibitor.

WNK463 是口服有活性的 WNK 激酶抑制剂，能够抑制 WNK1 (IC50:5 nM)、WNK2 (IC50:1 nM)、WNK3 (IC50:6 nM)及 WNK4 (IC50:9 nM)。