UrocortinIII, mouseTFA is a corticotropin-releasing factor (CRF)-related peptide. UrocortinIII preferentially binds and activates CRF-R2. UrocortinIII (Ucn3) is a known component of the behavioral stress response system. UrocortinIII and CRF-R2 in th
Mouse UcnIII is expressed predominantly in regions of the brain known to be involved in stress-related behaviours, and its expression in the hypothalamus increases following restraint.