transdermal peptide (td 1 (peptide))

Transdermal Peptide is a 11-amino acid peptide, binds to Na+ K+-ATPase beta-subunit (ATP1B1), and enhances the transdermal delivery of many macromolecules. Transdermal Peptide (TD1) binds to ATP1B1, and mainly interacts with the C-terminus of ATP1B1 in yeast and mammalian cells. The interaction affects the expression and localization of ATP1B1 and epidermal structure, but can be antagonized by the exogenous competitor ATP1B1 or be inhibited by ouabain. Inhibition of Transdermal Peptide binding to ATP1B1 causes decreased delivery of macromolecular drugs across the skin[1]. [1]. Wang C, et al. Role of the Na(+) K(+)-ATPase beta-subunit in peptide-mediated transdermal drug delivery. Mol Pharm. 2015 Apr 6;12(4):1259-67.

Transdermal Peptide TD-1 HCl 是一种用于增强透皮药物递送的新型肽，通过局部联合给药促进数种药物和大的亲水性蛋白质的穿透皮肤屏障，如胰岛素和人生长激素b。

Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA), an 11-amino acid peptide, specifically binds to the Na+ K+-ATPase beta-subunit (ATP1B1), predominantly interacting with its C-terminus. This compound is capable of enhancing the transdermal delivery of various macromolecules[1].

Transdermal Peptide TFA (TD 1 Peptide TFA) is an 11-amino acid polypeptide that binds to Na+ K+ -atpase beta-subunit (ATP1B1) and interacts with the C terminal of ATP1B1.Transdermal Peptide TFA can enhance the transmission of some large molecules in the s

Transdermal Peptide (TD 1 peptide) is a 11-amino acid peptide, binds toNa+ K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide can enhance the transdermal delivery of many macromolecules.Transdermal Pep

Transdermal Peptide acetate(888486-23-5 free base) (TD 1 (peptide) acetate) 是一种 11 个氨基酸的肽，与 Na+ K+-ATPase β 亚基 (ATP1B1) 结合，主要与 ATP1B1 的 C 端相互作用。透皮肽可以增强许多大分子的透皮传递。透皮肽 TD 1 酰胺是一种新型肽，旨在增强透皮药物传递。