Tos-PEG3-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tos-PEG3-NH-Boc (PROTAC Linker 9) is a PEG-based linker utilized for the synthesis of PROTACs. It plays a critical role in facilitating the connection between a target protein and an E3 ubiquitin ligase, ultimately leading to the degradation of the target protein.
Tos-PEG3-CH2COOtBu is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Azide-PEG3-Tos is a PEG-based PROTAC linker utilized in the synthesis of PROTACs[1]. It is a non-cleavable 3 unit PEG ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[2].