tetanus toxin

Tetanus Toxin (830–844) 是具有生物活性的肽类化合物。它是破伤风毒素衍生的 TT830–844 CD4+ T 细胞表位，能与多种 HLA-DRB 分子结合。该 CD4+ T 细胞表位由于与广泛的 HLA-DRB 分子具有亲和力，有潜力在大范围人群中诱发 CD4+ T 细胞应答。

Tetanus toxin (830-843) from tetanus toxoid is a universal human tetanus toxin T cell epitope. It induces T-cell activation and is used as a helper peptide in vaccinations.

Tetanus toxin 830-843 acetate (Tetanus toxin 830-843 acetate (119260-99-0 free base)) 来自破伤风类毒素的醋酸破伤风毒素(830-843) 是一种通用的人类破伤风毒素 T 细胞表位。它诱导 T 细胞活化并在疫苗接种中用作辅助肽。

Tetanus toxin peptide 是一种从 Clostridium tetani 的毒素中提取的特定肽段.该肽段可在小鼠体内作为免疫原,用于诱发糖尿病模型,进而支持1型糖尿病的科研工作.

Tetanus Toxin (830–844) TFA 是一种具生物活性的肽。(破伤风毒素衍生肽 TT830–844 CD4+T 细胞表位，该表位能结合多种 HLA-DRB 分子，因此有望在大多数人群中激活 CD4+T 细胞反应)。

Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit. It binds to the neurotoxins botulinum toxin serotype A (BTxA), BTxA heavy chain, and tetanus toxin with IC50 values of 11, 0.74, and 7.2 μM, respectively.[1] Ganglioside GT1b-containing liposomes bind to the major coat protein VP1 from Merkel cell polyomavirus (MCPyV), which has been identified in Merkel cell carcinomas, identifying ganglioside GT1b as a putative MCPyV receptor. [2] Ganglioside GT1b decreases production of IL-6, IL-10, IgG, IgM, and IgA in human peripheral blood mononuclear cells (PBMCs) by 31.4, 30.5, 60, 59.5, and 58%, respectively, when used at a concentration of 10 μM [3] . Ganglioside GT1b mixture contains ganglioside GT1b molecular species with C18:1 and C20:1 sphingoid backbones.

Siltartoxatug，一种IgG1κ型人源抗体，专门针对破伤风毒素(tetanus toxin)，其同型对照为HumanIgG1kappa, Isotype Control。

Influenza A NP (383-391) (HLA-B27) 是从破伤风毒素中提取的多肽序列.该序列作为CD4+ T 辅助细胞表位具有高免疫原性,有助于增强CD8+ 细胞毒性T淋巴细胞 (CTL) 的反应.此外,Influenza A NP (383-391) (HLA-B27) 也用于乳腺癌的研究工作中.