tco-peg8-tco

TCO-PEG8-TCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG8-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG8-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG8-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG8-TFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

(R)-TCO-PEG8-acid 是一种含有 8 个 PEG 单元的ADC Linker。其 TCO 基团能够与带有 Tetrazine 基团的分子进行逆电子需求 Diels-Alder?反应 (iEDDA)。

(S)-TCO-PEG8-NHS ester含有8个PEG单元，属于ADC Linker类化合物。该化合物的TCO基团能够与具备Tetrazine基团的分子进行逆电子需求 Diels-Alder反应(iEDDA)。'

Me-Tet-PEG8-NH2 (hydrochloride) 是一种含有 2 个 PEG 单元的 ADC Linker。该化合物通过其 Tetrazine 基团能够与含 TCO 基团的化合物发生特异性的逆电子需求 Diels-Alder 反应 (iEDDA)。

(R)-TCO-PEG8-NHS ester，作为一种含有 8 个 PEG 单元的 ADC Linker，其 TCO 基团能够与含 Tetrazine 基团的分子通过逆电子需求 Diels-Alder 反应 (iEDDA)进行有效结合。'

Me-Tet-PEG8-Maleimide 是一种包含 8 个 PEG 单元的 ADC Linker。Me-Tet-PEG8-Maleimide 能够通过其 Tetrazine 基团与具有 TCO 基团的化合物进行特异性的逆电子需求 Diels-Alder 反应 (iEDDA)。其马来酰亚胺基团 (-Maleimide) 在水介质中会降解，并用于药物递送研究。

Me-Tet-PEG8-NHBoc 是一种含有 8 个 PEG 单元的 ADC Linker。它利用自身的 Tetrazine 基团与具有 TCO 基团的化合物进行特异性的逆电子需求 Diels-Alder 反应 (iEDDA)。