TCO-PEG3-Biotin is a cleavable ADC linker comprised of three PEG units. It is primarily employed in the synthesis of ADCs, which are antibody-drug conjugates [1].
Biotin-PEG3-Me-Tet, an ADC linker consisting of three PEG units, utilizes its Tetrazine group to participate in a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds containing TCO groups.