tankyrasei

Tankyrase-IN-2 is a selective, potent and orally active inhibitor of tankyrase with IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectively

Tankyrase Inhibitors 49 is an effective, selective, and orally bioavailable inhibitor of tankyrase (IC50: 0.1nM).

Tankyrase Inhibitors 22 is a potent, selective, and orally bioavailable inhibitor of tankyrase (IC50: 0.1nM).

Tankyrase-IN-5（Compound 30f）作为MSC2504877的类似物，能有效抑制tankyaseTNKS1和TNKS2，其IC50分别为2.3 nM和7.9 nM。