sulfospdb

sulfo-SPDB is a cleavable linker vital in ADC synthesis. sulfo-SPDB joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.

Sulfo-SPDB-DM4 is a drug-linker conjugate designed for antibody-drug conjugates (ADCs) that employs the maytansine-based payload (DM4, an antitubulin agent) connected through the sulfo-SPDB linker.

Sulfo-SPDB-DGN462为一种ADC活性连接剂，毒素DGN462通过可裂解的Sulfo-SPDB linker偶联形成。DGN462是一种DNA烷基化剂，对抗肿瘤（如急性髓系白血病[AML]）表现出有效性。