Firzacorvir is a cyclic sulfamide compound that acts as an HBV core protein modulator and exhibits potent anti-HBV activity, with an EC50 value of < 1 μΜ.
DTP348 is an oral dual CAIX inhibitor radiosensitizer. DTP 348 is an oral dual drug with two mechanisms of action: (1). carbonic anhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide components; (2). radio sensitizer of hypoxic cells through its 5-nitroimidazole moiety.