sq 14534

Captopril (SA333) 是一种含巯基的，具有口服活性的血管紧张素转换酶(ACE)抑制剂 ，IC50=0.025 μM，广泛应用于高血压和充血性心力衰竭的研究。Captopril 也是NDM-1抑制剂，IC50=7.9 μM。

Epicaptopril (SQ 14534),一种Captopril的衍生物,主要作用为抑制血管紧张素转换酶(ACE).此外,Epicaptopril能增强依赖内皮源性舒张因子(EDRF)的血管舒张效果.作为自由基清除剂,它亦广泛应用于针对氧化应激和自由基损伤所致心血管疾病的研究.

Captopril EP Impurity E is an impurity of Captopril. Captopril, also known as SQ-14534, is an orally active angiotensin-converting enzyme (ACE) inhibitor that contains a thiol group. It has antihypertensive properties and competes with ACE with an inhibitor constant (IC 50 ) of 0.025 μM.

CaptoprilEPImpurity B 是一种 Captopril 的杂质。Captopril 是一种含巯基的口服活性血管紧张素转换酶(ACE)抑制剂 (IC50=0.025 μM)。