somatostatin-28

Somatostatin-28 (1-14) is an N-terminal fragment of the neuropeptide somatostatin-28, which originates from the posttranslational cleavage of prosomatostatin, derived from the larger precursor preprosomatostatin.

Somatostatin-28 (1-12) is a fragment of somatostatin that is monitored in brain tissue to track the processing of somatostatin.

Tyr-Somatostatin-28 是一种生长抑素，在 Somatostatin-28 的基础上添加了一个酪氨酸。

[Tyr12] Somatostatin 28 (1-14)，是Somatostatin-28 (1-14)的类似物，属于神经肽生长抑素-28的N-末端片段。

Somatostatin 1-28 acetate 在人源血浆中循环。 血浆中约 46% 的总生长抑素样免疫反应性是由于 Somatostatin 1-28 acetate 所致。

Cortistatin-29 is a neuropeptide that is structurally similar to somatostatin-28. It is produced by cleavage of preprocortistatin to procortistatin, which is cleaved at dibasic amino acids to form cortistatin-29 and cortistatin-14 as well as other partial cleavage products. Cortistatin mRNA is expressed in the human brain and in interneurons of the rat hippocampus and cerebral cortex. Cortistatin-29 binds to somatostatin (SST) receptors with IC50 values of 2.8, 7.1, 0.2, 3, and 13.7 nM for SST1-5, respectively. Cortistatin-29 is found at similar levels as cortistatin-14 in mouse AtT20 cells but is secreted at a lower level. Cortistatin-29 corresponds to residues 85-112 of the rat peptide sequence.

[Nle8] Somatostatin (1-28)为生长抑素(1-28)的衍生物，其特征在于第8位的甲硫氨酸被正亮氨酸所替代。该化合物能够促使淀粉酶的释放，并增加胰腺腺泡中的环AMP水平。

Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to inhibit the release of insulin and

Somatostatin receptor agonist, derived from the post-translational cleavage of prosomatostatin.