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sirreal1

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  • 抑制剂&激动剂
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    TargetMol | PROTAC
  • sirreal-1
    SirReal 1
    T24790801227-82-7
    SirReal-1 is an effective and selective inhibitor of Sirt2.
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    • ¥ 10600
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  • SirReal1-O-propargyl
    PROTAC Sirt2-binding moiety 1
    T186411862237-99-7
    SirReal1-O-propargyl is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 μM. SirReal1-O-propargyl, the SirReal1-based moiety, binds to the cereblon ligand via a linker to form PROTAC to degrade Sirt2[1].
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