sibiromycin

Sibiromycin, a glycosylated pyrrolobenzodiazepines (PBDs) compound, is a naturally occurring and potent antitumor antibiotic. It exerts its activity by covalently binding to DNA in the minor groove at the NH2 of guanine.

Sibiromycin (GMP)是 Sibiromycin 的 GMP 级别试剂。Sibiromycin 是一种糖基化的吡咯并苯二氮䓬类（PBDs）化合物，是一种天然存在的强效抗肿瘤抗生素。它通过与 DNA 在鸟嘌呤的氨基端的凹槽处形成共价键的方式发挥其活性。