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  • Sartorypyrone D
    T368751801167-48-5
    Sartorypyrone D is a fungal metabolite that has been found inN. fischeri.1It inhibits NADH fumarate reductase (NFRD; IC50= 1.7 μM inA. suummitochondria) and NADH oxidase (IC50= 3 μM in bovine heart mitochondria). Sartorypyrone is active against the Gram-positive bacteriaB. subtilis,K. rhizophila, andM. smegmatisin disc assays. 1.Kaifuchi, S., Mori, M., Nonaka, K., et al.Sartorypyrone D: A new NADH-fumarate reductase inhibitor produced by Neosartorya fischeri FO-5897J. Antibiot. (Tokyo)68(6)403-405(2015)
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  • Sartorypyrone A
    20-O-Acetylsartorypyrone D
    TN81351452396-10-9
    Sartorypyrone A (20-O-Acetylsartorypyrone D) 为从土壤真菌 Neosartorya fischeri 提取的单环子萜化合物.它在体外对 MCF-7、NCI-H460 及 A375-C5 细胞系展示了生长抑制活性,显示其具备抗癌的潜力.
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