s3304

S 3304 是一种新型的基质金属蛋白酶抑制剂，能够特异的抑制MMP-2和MMP-9的活性。

S-3304 is a n orally-agent agent with potential antineoplastic activity. S-3304 inhibits matrix metalloproteinases (MMPs), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis.

Tetrahydrocoptisine (STYLOPINE) 具有抑制炎症的有效作用。它通过抑制 NF-κB 信号通路对 LPS 诱导的 ALI 具有保护作用，这可能涉及抑制肺部炎症过程。它具有胃保护活性，归因于减少 NO 产生和调节促炎细胞因子，抑制中性粒细胞积累和 NF-κB 表达。它是一种活性抗炎成分，通过下调 NF-κB 活化、磷酸化 ERK1 2 和磷酸化-p38MAPK 信号通路抑制 TNF-α、IL-6 和 NO 的产生。

MMI-166 is a selective matrix metalloproteinase (MMP) inhibitor that prevents tumor invasion and metastasis by downregulating the activity of MMP-2 and MMP-9.