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  • 抑制剂&激动剂
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    TargetMol | Inhibitors_Agonists
  • Topiramate
    托吡酯, RWJ 17021, McN 4853
    T067597240-79-4
    Topiramate (RWJ 17021) 是一种GluR5受体拮抗剂,可通过增强GABAergic 活性,抑制kainate AMPA 受体,抑制钠和钙通道的电压敏感,增加钾电导并抑制碳酸酐酶来产生抗癫痫作用,用于治疗部分性和全身性癫痫发作。
    • ¥ 197
    现货
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  • TargetMol
    Topiramate lithium
    T61145488127-53-3
    Topiramate lithium (McN 4853) is a wide-ranging antiepileptic compound with GluR5 receptor antagonistic properties. Its mechanism of action involves enhancing GABAergic activity, inhibiting kainate/AMPA receptors, voltage-sensitive sodium and calcium channels, and increasing potassium conductance. Additionally, this compound inhibits carbonic anhydrase. [1][2][3]
    • ¥ 10600
    6-8周
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