reticulol

Reticulol is an isocoumarin derivative produced by certain species of Streptomyces. Reticulol inhibits cAMP phosphodiesterase (IC50 = 41 µM). Recticulol (M.W. 222.2) exhibits a potent in vitro cytotoxicity against the human lung tumor cell line A427 and the mouse melanoma cell line B16F10.

6-O-Methylreticulol是一种异香豆素(isocoumarin)及真菌代谢产物，已在S. mobaraensis中被发现。