remdesivird5

Remdesivir-D5 is a deuterium labeled Remdesivir. Remdesivir is a nucleoside analogue, with effective antiviral activity.

Remdesivir-d4 是 Remdesivir 的氘代化合物。Remdesivir 的 CAS 号为 1809249-37-3。Remdesivir是一种核苷类似物，具有抗病毒活性，在 HAE 细胞中，对SARS-CoV和MERS-CoV的EC50值为 74 nM，有潜力用于 2019-nCoV (COVID-19) 研究。

Remdesivir, also known as GS-5734, is a prodrug form of the antiviral nucleoside analog GS-44152. Remdesivir is a broad spectrum anti-viral drug that has shown to inhibit SARS-CoV-2, in vitro and in vivo. Efficacy of remdesivir against Ebola virus has been demonstrated. Remdesivir inhibits SARS-CoV-2 replication, reduces viral load, and exerts protective effects in SARS-CoV-2 infected animals. Remdesivir also reduces the pathological process, alleviates mild symptoms, and improves pulmonary lesions in SARS-CoV-2-infecetd animals. Remdesivir has been used as a compassionate drug for treating COVID-19 patients. *******WARNING****** Our product remdesivir is a pure chemical solid powder which is only for laboratory research use, NOT FOR HUMAN OR PATIENT USE

Remdesivir (GS-5734) 是一种核苷类似物，一种广谱的抗病毒化合物，通过抑制病毒的 RNA 依赖性 RNA 聚合酶发挥活性。Remdesivir 对埃博拉病毒、SARS 病毒、MERS病毒等均有活性，对 COVID-19 有潜在治疗价值。

Remdesivir de(ethylbutyl 2-aminopropanoate) 是 Remdesivir 的一种杂质，后者为一种具有抗病毒活性的核苷类似物。在 HAE 细胞针对 SARS-CoV 和 MERS-CoV 的实验中，Remdesivir 的 EC50 值为 74 nM；在针对鼠肝炎病毒的延迟脑肿瘤细胞实验中，其 EC50 值为 30 nM。此外，Remdesivir 亦被认为具有针对 2019-nCoV (COVID-19) 的研究潜力。