r-4050

Pipamperone acts as an antagonist of the 5-HT2A, 5-HT2B, 5-HT2C D2, D3, D4, α1-adrenergic, and α2-adrenergic receptors. It shows much higher affinity for the 5-HT2A and D4 receptors over the D2 receptor (15-fold in the case of the D4 receptor, and even hi

Pipamperone (McN-JR 3345) 是5-HT2A 受体和D4受体的高亲和力拮抗剂，也是D2受体的低亲和力拮抗剂，pKi 分别为 8.2、8.0 和 6.7。