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    TargetMol | Inhibitors_Agonists
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    TargetMol | PROTAC
  • PROTAC Sirt2 Degrader-1
    T166672098487-75-1
    PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1 Sirt3 (IC50s > 100 μM)[1].
    SirtuinPROTACs
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