protac cdk2/9 degrader-1

PROTAC CDK2 9 Degrader-1 is a potent CDK2 and CDK9 dual degrader(DC50 of 62 nM and 33 nM).

NH2-C2-amido-C2-Boc is an alkyl ether-based PROTAC linker employed in the synthesis of various PROTACs, including the PROTAC CDK2 9 Degrader-1[1]. NH2-C5-NH-Boc can also serve as a suitable precursor for the synthesis of these PROTACs.

Thalidomide-C2-amido-C2-COOH is a compound that includes a CRBN ligand for the E3 ubiquitin ligase, as well as a linker. It is utilized in the development of PROTAC CDK2 9 Degrader-1[1].