propargyl-peg3-azide

Propargyl-PEG3-amine is a PEG derivative containing a propargyl group and an amino group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper-catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

Azido-PEG3-S-PEG4-propargyl is a polyethylene glycol (PEG)-based linker that contains the azide group and propargyl functionality. This linker is designed specifically for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Amino-PEG4-bis-PEG3-propargyl 是一种很具特色的点击化学试剂，它由6个单元的PEG组成，并带有可降解性质，适合用作合成抗体偶联活性分子（ADC）的链接器。该化合物包含一个Alkyne 基团，能够在铜催化下与含Azide基团的分子进行叠氮-炔环加成反应（CuAAc）。