Propargyl-PEG4-O-C1-NHSester, also known as compound 8, is a polyethylene glycol (PEG)-based linker that serves as a reactive functional group for the synthesis of proteolysis targeting chimeras (PROTACs).
Propargyl-O-C1-amido-PEG4-C2-NHSester is a non-cleavable 4-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.