orexin a (human, rat, mouse)

Orexin A human, rat, mouse, a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A human, rat, mouse has been used to study its effect on the functioning of porcine pancreatic islets. It has also been used as an orexin receptor 1 (OX1R) agonist to study the effect of orexin systems in the effect of etonogestrel on respiratory response to prolonged metabolic acidosis.

Endogenous agonist at orexin receptors (Ki values are 20 and 38 nM for OX1 and OX2 receptors respectively). Stimulates feeding following central administration and may be involved in the control of sleep-wake cycle and other hypothalamic functions.

Orexin A (human, rat, mouse) acetate (Hypocretin-1 (human, rat, mouse) acetate) 是一种具有镇痛特性的兴奋性神经肽，可激活 Orexin-1 受体 （OX1R） 和 Orexin-2 受体 （OX2R），可用于研究神经系统疾病。