oleic acid 13c

Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been found in human plasma, cell membranes, and adipose tissue.1,2 It contributes approximately 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets.1 Oleic acid inhibits collagen-stimulated platelet aggregation by approximately 90% when used at a concentration of 10 μg/ml. It also inhibits fMLF-induced neutrophil aggregation and degranulation by 55 and 68%, respectively, when used at a concentration of 5 μM, similar to arachidonic acid .3 Oleic acid (60 μM) induces release of intracellular calcium in human platelets.4

Oleic acid-13C18是一种13C标记的Oleic acid。Oleic acid (9-cis-Octadecenoic acid) 是存在于人类脂肪细胞及其他组织中的最常见的单不饱和脂肪酸，且作为Na+/K+ATP酶的激活剂。

Palmitoleic acid-13C16 是一种含有 13C 标记的 Palmitoleic acid。作为脂肪酸的组成部分，Palmitoleic acid 可以降低 SHRSP 大鼠因脑血管疾病致死的风险。

Linoleic acid-13C1是13C标记的Linoleic acid。这种多不饱和脂肪酸（PUFA）常见于植物油、坚果和种子中。Linoleic acid是膜磷脂的一部分，能够作为膜流动性的结构成分维持表皮透皮水屏障。它通过氧化作用造成红细胞和血红蛋白的损伤。