ochratoxin a 13c20

Ochratoxin A-13C20 is intended for use as an internal standard for the quantification of ochratoxin A by GC- or LC-MS. Ochratoxin A (T75659) is a mycotoxin that has been found inAspergillusandPenicillium.1It increases lipid peroxide levels and the number of apoptotic cells,as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 μg/kg.2Topical application of ochratoxin A (80 μg/mouse)induces DNA damage,cell cycle arrest at the G0/G1phase,and apoptosis in mouse skin cells.1It also initiates tumor formation in a two-stage mouse skin tumorigenesis model. Ochratoxin A (T75659)has been found as a contaminant in a variety of foods.3

Ochratoxin A (赭曲霉毒素 A) 属于霉菌毒素类，是由曲霉属 (Aspergillus) 和青霉属 (Penicillium) 物种产生的一种常见的次级代谢产物。Ochratoxin A 具有显著的肾毒性、免疫毒性、致畸性和致癌潜力，其生化机制涉及诱导细胞内自由基的产生并引发严重的氧化损伤。

Ochratoxin α (Ochratoxin alpha)是一种 Ochratoxin A 的降解产物，可用于研究 Ochratoxin A 降解。