netropsin

Netropsin is a basic polypeptide isolated from Streptomyces netropsis with antibiotic and antiviral activity. It is strong, specific binding to A-T areas of DNA is useful to genetics research. Netropsin is active against Gram-negative bacteria and Gram-po

Netropsin dihydrochloride is a small-molecule MGB (minor-groove binder), inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei.