mosapride

Mosapride (AS-4370) 是一种促胃肠动力药，是选择性5HT4激动剂。

Mosapride Citrate (TAK-370 citrate) 是一种促胃肠动力药，用作选择性 5HT4 激动剂。

Mosapride Citrate is a 5-HT4 receptor agonist used to stimulate gastrointestinal motility via acetylcholine. Mosapride Citrate facilitates acetylcholine release from the enteric cholinergic neurons.

Des-4-fluorobenzyl Mosapride, the main metabolite of mosapride, acts as a gastroprokinetic agent improving upper gastrointestinal (GI) motility by stimulating the serotonin receptor 4 (5-HT4; EC50= 74.2 nM, in guinea pig ileal longitudinal muscle myenteric plexus). It has been shown to increase colonic motility in dogs, horses, and guinea pigs in vivo. Mosapride, including this metabolite, is utilized in human and veterinary medicine to mitigate post-surgical and Parkinson's-induced constipation.

Mosapride N-Oxide 是 Mosapride 的主要活性代谢物 (metabolite)。Mosapride 是一种胃促运动剂，可作为选择性 5HT4 激动剂。

Mosapride-d5 是 Mosapride 的氘代化合物。Mosapride 的 CAS 号为 112885-41-3。Mosapride是一种促胃肠动力药，是选择性5HT4激动剂。

Des-4-Fluorobenzyl Mosapride-d5 是 Des-4-Fluorobenzyl Mosapride 的氘代化合物。Des-4-Fluorobenzyl Mosapride 的 CAS 号为 152013-26-8。