ml-323

ML323 是一种有效的可逆的USP1-UAF1抑制剂，在Ub-Rho 测定实验中，IC50为 76 nM。在使用 K63 连接的双泛素 (di-Ub) 和单泛素化 PCNA 的正交凝胶测定中(Ub-PCNA)分别作为底物。

Tannic acid (Gallotannic acid) 属于多酚类天然产物，是一种 hERG 通道阻塞剂，也是一种 CXCL12 CXCR4 抑制剂。Tannic acid 具有抗菌、抗氧化、抗炎和抗肿瘤等多种生物活性。

4-Chloroguaiaco (4-Chloro-2-methoxyphenol) is a phenol derivative, with antimicrobial activity. 4-Chloroguaiaco shows inhibition against S. aureus and E. coli with MICs of both 110 μg mL[1]. [1]. Patrícia Fontes Pinheiro, et al. Semisynthetic Phenol Derivatives Obtained from Natural Phenols: Antimicrobial Activity and Molecular Properties. J Agric Food Chem. 2018 Jan 10;66(1):323-330.