ML 190 is a potent and selective κ opioid receptor (KOR) antagonist (Ki=129 nM), exhibiting an IC50=150 nM in β-arrestin assays, suitable for studying drug addiction.
NC190 is an inhibitor of topoisomerase II that inhibited the growth of FM3A cells in clinical trials. NC-190 strongly inhibited the growth of FM3A cells when cultured with NC-190 for 48 h (IC50: 0.019 μg/ml). NC-190 potently suppressed DNA synthesis with