mcm 2

5-Methoxycarbonylmethyl-2'-O-methyluridine is a 5-modified pyrimidine nucleoside; 2'-O-Methyl nucleoside.

DAPTA (Adaptavir) 是一种合成肽，是 CCR5抑制剂，有抗 HIV 的活性。

LY3177833 抑制CDC7和pMCM2，IC50值分别为 3.3 nM 和 290 nM。

LY3143921 ((S)-Example 2) hydrate 是一种具有口服活性的 CDC7激酶抑制剂。LY3143921 hydrate 表现出广泛的体外抗癌活性。

Cdc7-IN-8, a potent inhibitor, targets Cdc7, a serine threonine kinase responsible for activating MCM promotion through phosphorylation of the microchromosome maintenance protein (MCM protein). MCM protein, an essential component of DNA replication initiation, plays a crucial role. Cdc7-IN-8 holds promise in cancer disease research (WO2021032170A1, compound 1-1 1-2) [1].