manassantin a

Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX PGE2 stimulation, inhibition of iNOS production and NF-κB act

Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA p65 subunit of NF-κB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in part, via inhibition of cell proliferation and decrease of collagen production.

4-O-Demethylmanassantin A 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T123894，CAS号为 943011-47-0。