mal-peg4-vc-pab-dmea

Mal-PEG4-VC-PAB-DMEA is a cleavable ADC linker that incorporates a Maleimide moiety. It is employed in the synthesis of antibody-drug conjugates (ADCs)[1].

Mal-PEG4-VC-PAB-DMEA TFA 是一种含 Maleimide 基团的可降解ADC linker，适用于合成抗体偶联活性分子 (ADC)。

Mal-PEG4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) therapy. It combines the ADC linker, Mal-PEG4-VC-PAB, with the potent ADC cytotoxin, DMEA-PNU-159682. The cytotoxin, DMEA-PNU-159682, is derived from metabolites of nemorubicin (MMDX) found in liver microsomes, as well as the ADC cytotoxin PNU-159682[1].

Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is an antibody-drug conjugate linker that incorporates the antitumor antibiotic Duocarmycin SA, connected through the Mal-PEG4-VC-PAB-DMEA-Seco linker, for targeted cancer therapy.

Mal-PEG4-VC-PAB-DMEA-duocarmycin SA 是一种硫醇反应型 Drug-linker,duocarmycin SA 是一种非常有效的、具有口服活性的细胞毒性剂，可用于抗体-药物偶联物（ADC）的合成。

Mal-PEG4-VC-PAB-DMEA-duocarmycin-DM 是一种硫醇反应型 Drug-linker,Duocarmycin DM 是一种 DNA 小沟烷基化剂，可作为 ADC 结合物毒素，用于抗体-药物偶联物（ADC）的合成。

C-lock-G5-DUO-5 是一种 Drug-linker，DUO-5 是一种微管抑制剂、新型的毒素分子，具有抗癌活性，与 C-lock-G5 采用稳定共价不可逆连接方式,重新引入共价键联接，更好的稳定性,改进的 PK 特性。