mage-3

MAGE-3 (271-279) is a peptide consisting of 271-279 amino acid residues that is derived from melanoma antigens encoded by the MAGE-3 gene. It is specifically recognized by cytolytic T lymphocytes (CTLs) and binds to the human leukocyte antigen (HLA)-A2 molecule. MAGE-3 is highly expressed in various human tumor types, such as malignant melanoma, but not in normal tissues, except for the testis and placenta.

MAGE-3 Antigen (167-176) (human) 是一个由 MAGE-A3 编码并与 HLA-B44 抗原结合的人类抗原决定簇，包含8个氨基酸的多肽序列。

This peptide MAGE-3-encoded HLA-A24 epitope is a high MHC binder.The identification of this MAGE-3 HLA-A24 peptide may as a result effectiveially offer the opportunities to design peptide-based immunotherapeutic approaches that might prove to be potent in