m-122

M122 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.

M133 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.

ZZM-1220是一种针对组蛋白赖氨酸甲基转移酶G9a GLP的共价抑制剂，IC50值分别为458 nM和924 nM。该化合物能有效抑制H3K9me2在细胞中的作用，从而显著促进三阴性乳腺癌(TNBC)细胞的凋亡(apoptosis)，同时在G2 M期阻断细胞周期的进程。

Antifungalagent 122 (compound 201)，一种高效广谱抗真菌剂。该化合物可阻止真菌相变及生物膜形成，并能抑制CYP3A4-M和CYP3A4-T酶活性，其IC50值分别为2.11 µM和4.53 µM。此外，Antifungalagent 122不具细胞毒性。

Carotenoid mixture is a mixture of carotenoids that contains the antioxidative and anti-inflammatory carotenoid capsanthin and the antioxidative vitamin A precursor β-carotene , as well as additional carotenoids and carotenoid esters.1,2,3,4 1.Kim, J.S., Lee, W.M., Rhee, H.C., et al.Red paprika (Capsicum annuum L.) and its main carotenoids, capsanthin and β-carotene, prevent hydrogen peroxide-induced inhibition of gap-junction intercellular communicationChem. Biol. Interact.254146-155(2016) 2.Narisawa, T., Fukaura, Y., Hasebe, M., et al.Prevention of N-methylnitrosourea-induced colon carcinogenesis in rats by oxygenated carotenoid capsanthin and capsanthin-rich paprika juiceProc. Soc. Exp. Biol. Med.224(2)116-122(2000) 3.Horie, S., Okuda, C., T., Y., et al.Purified canola lutein selectively inhibits specific isoforms of mammalian DNA polymerases and reduces inflammatory responseLipids45(8)713-721(2010) 4.Negishi, H., Ueda, Y., and Azuma, M.Antioxidant fat-soluble vitamins and lipid peroxides in serumJ. Clin. Biochem. Nutr.26227-234(1999)