linezolid-d-3

Linezolid-D3是Linezolid（T0391）的氘代标记物，可用于同位素示踪。Linezolid是一种用于阻断细菌蛋白质合成起始过程的合成抗生素。Linezolid-D3可用于抗菌药代动力学及基于示踪的生化研究体系，以研究蛋白质合成抑制机制及细菌翻译模型中的抗生素分布同位素追踪。

Linezolid-D3 (Standard) 是 Linezolid-D3 的标准品，适用于定量分析、质量控制及生化实验等相关研究。Linezolid D3 是Linezolid的氘标物，它是一种人工合成的抗生素，旨在阻止细菌蛋白质合成的启动过程。

CAY10742 is an orally bioavailable oxadiazole antibiotic.1It is active against the Gram-positive bacteriaS. aureus,S. epidermidis,S. haemolyticus,B. cereus,B. licheniformis,E. faecalis, andE. faecium(MICs = 1-4 μg/ml), including laboratory strains and clinical isolates with varying degrees of resistance to methicillin, vancomycin, linezolid, and other antibiotics. CAY10742 (40 mg/kg) reduces the number of bacteria in mouse neutropenic thigh models of linezolid-sensitive or -resistant methicillin-resistantS. aureus(MRSA) infection. 1.Boudreau, M.A., Ding, D., Meisel, J.E., et al.Structure-activity relationship for the oxadiazole class of antibacterialsMed. Chem. Lett.11(3)322-326(2019)