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L-Carnitine hydrochloride ((R)-Carnitine hydrochloride) 是一种高极性的双离子小分子，是线粒体 β-氧化的重要辅因子。L-Carnitine hydrochloride 促进长链脂酰辅酶 A 转运至线粒体以进行 β-氧化降解，辅助细胞能量代谢。L-Carnitine hydrochloride 还具有抗氧化活性，可缓解多种先天性代谢异常引起的代谢失衡，是代谢研究中的重要工具化合物。

Sarolaner (PF-6450567) 是一种可口服的广谱外寄生虫剂，有效抑制狗身上的跳蚤和虱子，对C. felis 的 LC80值为 0.3 μg/mL，对O. turicata 的 LC100值为 0.003 μg/mL。

Ochratoxin A-13C20 is intended for use as an internal standard for the quantification of ochratoxin A by GC- or LC-MS. Ochratoxin A (T75659) is a mycotoxin that has been found inAspergillusandPenicillium.1It increases lipid peroxide levels and the number of apoptotic cells,as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 μg/kg.2Topical application of ochratoxin A (80 μg/mouse)induces DNA damage,cell cycle arrest at the G0/G1phase,and apoptosis in mouse skin cells.1It also initiates tumor formation in a two-stage mouse skin tumorigenesis model. Ochratoxin A (T75659)has been found as a contaminant in a variety of foods.3

Racecadotril-D5 is intended for use as an internal standard for the quantification of racecadotril by GC- or LC-MS. Racecadotril (T1176) is a prodrug form of the neprilysin (NEP)inhibitor thiorphan. In vivo,racecadotril reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in rats when administered at doses of 80 or 100 mg/kg,respectively. It also decreases the duration of diarrhea and increases body weight gain in a neonatal gnotobiotic pig model of human rotavirus-induced diarrhea. Formulations containing racecadotril have been used in the treatment of acute diarrhea.

Oxaliplatin-D10 is intended for use as an internal standard for the quantification of oxaliplatin by GC- or LC-MS. Oxaliplatin (T0164) is a platinum-containing DNA-crosslinking agent. It induces the formation of DNA inter- and intrastrand crosslinks and DNA-protein adducts,inhibits DNA and RNA synthesis,and induces apoptosis in cancer cells. Oxaliplatin (T0164) is cytotoxic to cisplatin-sensitive A2780 (1A9)and KB-3-1 cells and cisplatin-resistant A2780-E (80)and KB-CP20 cells (IC50s = 0.12,0.39,4.7,and 2.7 µM,respectively). It reduces tumor growth in an HCCLM3 mouse xenograft model when administered at doses of 5 or 10 mg/kg once per week. Formulations containing oxaliplatin have been used in the treatment of advanced colorectal cancer and as adjuvants in stage III colon cancer.