lb80317

LB-80317, a DNA polymerase inhibitor, is used potentially for the potential treatment of hepatitis B virus infection.

Besifovir Dipivoxil (LB80380) maleate is an oral prodrug of LB80317. Besifovir Dipivoxil maleate is effective in hepatitis B virus (HBV) DNA suppression for both treatment-naive and lamivudine-resistant chronic hepatitis B (CHB) patients.

Besifovir 是由 LB80380 转化而来的一种 LB80380 母体药物，进一步代谢为其活性形式 LB80317。LB80380 是抗乙型肝炎病毒的抗病毒药物。