ibotenic acid, d-

D-Ibotenic Acid is a chemical compound and psychoactive drug which occurs naturally in Amanita muscaria and related species of mushrooms typically found in the temperate and boreal regions of the northern hemisphere. It is a conformationally-restricted analogue of the neurotransmitter glutamate, and due to its structural similarity to this neurotransmitter, acts as a non-selective glutamate receptor agonist. Because of this, ibotenic acid can be a powerful neurotoxin, and is employed as a brain-lesioning agent through cranial injections in scientific research.

Ibotenic acid (RS-42358-197) 对 N-甲基-D-天冬氨酸 (NMDA) 和反式-ACPD 或代谢型使君子氨酸 (Qm) 受体位点具有激动剂活性。