homofolic acid

Homofolic acid is a folic acid analog.

Tetrahydrohomofolic acid is a thymidylate synthetase inhibitor, antibacterial, and antimalarial agent.

11-Deazahomofolic acid is a phosphoribosylglycinamide formyltransferase inhibitor.

11-Oxahomofolic acid is a potential antitumor drug.

5,6,7,8-Tetrahydro-8-deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.

8-Deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.

Dihydrohomofolic acid is a substrate for dihydrofolate reductase that produces tetrahydro-homo folate which in turn suppresses thymidylate synthetase and then DNA synthesis.

Homopteroic Acid is an intermediate in the synthesis of Homofolic Acid which inhibits the growth of L1210 mouse leukemia cells when intracellular folates are acquired via the high-affinity folate binding protein.