h l photo lysine hydrochloride

H-L-Photo-lysine hydrochloride, a photo-cross-linker, is a diazirine-containing lysine amino acid. It can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells.

DiAzKs 是一种含二氮烯基团的赖氨酸类似物，作为光交联氨基酸可被位点选择性地引入蛋白质中，在光激活后实现蛋白–蛋白相互作用的共价捕获。该化合物广泛应用于体外及活细胞体系，用于研究动态分子相互作用、结构生物学以及具有高时空分辨率的互作组图谱绘制。