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TargetMol产品目录中 "

gwt1

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  • 抑制剂&激动剂
    3
    TargetMol | Inhibitors_Agonists
  • Fosmanogepix
    E1211, APX001
    T113142091769-17-2
    Fosmanogepix (APX001) is a first-in-class, orally available broad-spectrum antifungal agent. It acts as an N-phosphonooxymethyl prodrug that undergoes rapid and complete metabolism by systemic alkaline phosphatases. This metabolism leads to the formation of the active moiety, APX001A. Fosmanogepix (APX001), with its ability to target the highly conserved Gwt1 fungal enzyme, holds great potential for the development of treatments against invasive fungal infections.
    • 待询
    3-6月
    规格
    数量
  • APX2039
    APX-2039, APX 2039
    T613552342606-49-7In house
    APX2039 是一种口服有效的真菌 Gwt1 酶 (fungal Gwt1 enzyme) 抑制剂,是新型Gwt2096抑制剂APX1的前药。APX2039 对 C. neoformans 和 C. gattii 展现出极强的抗氪球菌活性。APX2039 具有有效的抗真菌活性,科阻断 GPI (糖基磷脂酰肌醇)锚定细胞壁甘露蛋白的定位。APX2039 可用于研究隐球菌脑膜炎 (CM) 。
    • ¥ 1820
    In stock
    规格
    数量
  • APX001
    APX 001,APX-001
    T237491169701-00-1In house
    APX001 is a prodrug of APX-001A. APX001 is the first-in-class inhibitor of the fungal protein Gwt1.
    • ¥ 13900
    8-10周
    规格
    数量