Grifolicacid is a natural carbonic anhydrase Ⅱ inhibitor(CAⅡ), it shows in-hibitory activities against CAⅡ with IC50 of 6.37 umol L. Grifolicacid has antibacterial activity, it can inhibit the growth of Staphylococcus aureus and Staphylococcus epidermid
4-O-Methylgrifolicacid is a natural inhibitor of carbonic anhydrase II (CAⅡ), exhibiting inhibitory activities against CAⅡ with IC50 values ranging from 6.37 to 71.73 μmol L.