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抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP1574	Gp100 (619-627) Gp100 619-627
	This is a HLA-A*0201 restricted epitope used in melanoma studies.
T39569	Gp100 (25-33), mouse Mgp100 (25-33),Gp100 (25-33), mouse
	Gp100 (25-33) corresponds to residues 25 to 33 of the mouse self/tumor antigen glycoprotein (mgp100), which is an enzyme responsible for pigment synthesis. This epitope fragment is found in both normal melanocytes and melanoma cells.
TP1416	Gp100 (25-33), human TFA (212370-40-6 free base) Gp100 (25-33), human TFA
	Gp100 (25-33), human TFA is a 25-33 amino acid fragment of human melanoma antigen.Gp100 (25-33), human TFA is a 9-amino acid (AA) epitopes restricted by h-2db and recognized by T cells.
TP1727	Gp100 (25-33), human
	Gp100 (25-33), human is the amino acids 25-33 fragment of the human melanoma antigen. It is a 9-amino acid (AA) epitope restricted by H-2Db and recognized by the T cells.This is amino acids 25 to 33 fragment of human melanoma antigen gp100. This H-2Db res
TP1543L	G280-9 acetate(156761-76-1 free base)	Others	Others
	G280-9 acetate(156761-76-1 free base) 是一种常见的黑色素瘤 gp100 表位，受 MHC 相关 HLA-A2 限制。 G280-9 序列是独特的，因为它可以在非常低的浓度下被细胞毒性 T 淋巴细胞识别，但是它显示出低的总免疫原性，这可能是由于该肽对 HLA-A2 的亲和力相对较低。
T76843	Tebentafusp
	Tebentafusp (IMCgp100) 是靶向 gp100（一种黑色素瘤相关抗原）的双特异性融合蛋白。该药物通过其 T 细胞受体 (TCR) 高亲和力结合域以及抗 CD3 T 细胞接合域，指引 T 细胞针对表达 gp100 的肿瘤细胞进行杀伤。进一步，Tebentafusp 促进炎症细胞因子和细胞溶解酶的释放，直接导致肿瘤细胞裂解。
TP1543	G280-9
	The G280-9 peptide, a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it shows low total immunogenicity that may

化合物

Gp100 (619-627)

Cat.No: TP1574

Synonym: Gp100 619-627

Target:

Gp100 (25-33), mouse

Cat.No: T39569

Synonym: Mgp100 (25-33),Gp100 (25-33), mouse

Target:

Gp100 (25-33), human TFA (212370-40-6 free base)

Cat.No: TP1416

Synonym: Gp100 (25-33), human TFA

G280-9 acetate(156761-76-1 free base)

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01540	HLA-A*02:01&B2M&GP100 (YLEPGPVTA) Tetramer Protein, Human, MHC (His & Avi) HLA0201,P100,MHC I,gp100,Glycopro...	Human	HEK293 Cells
	Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is involved in melanosome maturation. The Human HLA-A0201 gp100 (YLEPGPVTA) complex Protein is a complex of HLA-A0201 of the MHC Class I, B2M and YLEPGPVTA peptide of the gp100.
TMPK-01551	HLA-A02:01&B2M&GP100 (YLEPGPVTA) Monomer Protein, Human, MHC (His & Avi) MHC I,ME20-M,Glycoprotein 100*,gp100	Human	HEK293 Cells
	Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is involved in melanosome maturation. The Human HLA-A0201 gp100 (YLEPGPVTA) complex Protein is a complex of HLA-A0201 of the MHC Class I, B2M and YLEPGPVTA peptide of the gp100.
TMPK-01476	HLA-A24:02&B2M&GP100 Intron 4 (VYFFLPDHL) Monomer Protein, Human, MHC (His & Avi) HLA-A24:02,P100,Glycoprotein 100,GP	Human	HEK293 Cells
	Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is involved in melanosome maturation. The Human HLA-A0201 gp100 (YLEPGPVTA) complex Protein is a complex of HLA-A0201 of the MHC Class I, B2M and YLEPGPVTA peptide of the gp100.
TMPK-01475	HLA-A24:02&B2M&GP100 Intron 4 (VYFFLPDHL) Monomer Protein, Human, MHC (His & Avi), Biotinylated HLA-A24:02,Intron 4,gp100,GP...	Human	HEK293 Cells
	Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is involved in melanosome maturation. The Human HLA-A0201 gp100 (YLEPGPVTA) complex Protein is a complex of HLA-A0201 of the MHC Class I, B2M and YLEPGPVTA peptide of the gp100.
TMPK-01553	HLA-A*02:01&B2M&GP100 (YLEPGPVTA) Monomer Protein, Human, MHC (His & Avi), Biotinylated HLA0201,ME20-M,gp100,MHC I,Glycoprotein	Human	HEK293 Cells
	Glycoprotein 100, gp100 or Melanocyte protein PMEL is 661 amino acids long and is a type I transmembrane glycoprotein enriched in melanosomes, which are the melanin-producing organelles in melanocytes. This protein is involved in melanosome maturation. The Human HLA-A0201 gp100 (YLEPGPVTA) complex Protein is a complex of HLA-A0201 of the MHC Class I and YLEPGPVTA peptide of the gp100.