Folitixorin calcium, (6R)- is the calcium salt of Folitixorin, a substrate used by the enzyme methylenetetrahydrofolate reductase to generate 5-methyltetrahydrofolate.
Arfolitixorin sulfate, a potent 5-Fluorouracil (5-FU) moderator, is an immediately active form of Folate, [6R]-5,10-methylenetetrahydrofolate ([6R]-MTHF), and is potent for research on metastatic colorectal cancer [1].